iMembrane

Homology-Based Prediction of a Protein's Insertion into the Membrane

For Academic Use Only.

Need a test input? Try PDB entry 2JAF.

structure sequence

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Choosing "fast" will do a sequence search with BLAST and then re-align by structure superposition.
Choosing "thorough" will search directly with structure superposiiton. This is a lot slower, but gives more hits.

MAMMOTH Z-score cut-off:

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profile individual

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When choosing "profile", the first sequence will be considered the master sequence, which is to be
annotated. All sequences will be used to build a PSI-BLAST sequence profile, which will be used to
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Choosing "individual" will yield the same results as running iMembrane on each sequence separately
(but all results are listed on the same page).

BLAST E-value cut-off:

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